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Saturday, March 24, 2007

Association of Alcohol Craving With α-Synuclein (SNCA)


Studies have found that genomic variation in the gene SNCA, which encodes the protein α-synuclein, may contribute to the variation in alcohol consumption in an inbred rat model of alcohol preference. Studies in humans have provided support for an association between SNCA and craving for alcohol.

These results suggest that variation in SNCA contributes to alcohol craving, a common, although not uniform, feature of alcohol dependence.

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