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Saturday, January 5, 2008

Dose-response relation between volume of drinking and alcohol-related diseases in male general hospital inpatients
Alcohol and Alcoholism Advance Access published online on November 25, 2007



Previous studies investigating dose-response relations between volume of drinking and diseases have focused on single diseases only. Until now, the relation between the drinking volume and the risk of having any alcohol-attributable disease is largely unknown.

The aim of the present study is to investigate to what extent is the risk of diseases with different alcohol-attributable fractions (AAFs) predicted by daily alcohol consumption (> 120 g, 61–120 g vs 31–60 g).

In our sample, 26.6% of the inpatients showed a disease with AAF = 1, while 20.2% had a disease with AAF <> consuming > 120 g, and inpatients consuming 61–120 g revealed significantly higher odds for diseases with AAF = 1 compared to inpatients consuming 31–60 g (OR = 6.30, CI = 3.55–11.26; OR = 2.91, CI = 1.64–5.13).

Regarding diseases with AAF <> 120 g revealed significantly higher odds compared to the inpatients consuming 31–60 g (OR = 1.97, CI = 1.15–3.37).

A dose-response relation between the level of the drinking volume and the risk of diseases with AAF = 1 was found in this sample of inpatients from the general hospitals.


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